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Thyroiditis TgAA elevated serum levels of the majority of cases, while only 20-40% T3 AA cases And / or have elevated circulating T4. The elevated T3 AA And / or confirm the presence of T4 in the diagnosis of autoimmune thyroiditis, but spread underestimates, negative (non-elevated) as not rule out thyroiditis autoantibody. TgAA level measure allows the early detection of diseases, and facilitate genetic counseling. Affected dogs should not be used for breeding.
TgAA tests lead to false negative results announced in the last 90 days, the dog can get to the thyroid dose, the treatment of dogs tested during the unscrupulous owners, general, health record certification or, like tell the OFA thyroid registry. About 5% of dogs can be found in the TgAA false-negative results, a high T3AA and / or are T4AA. In addition, false positive results if the dog has been vaccinated in the last 30-45 days, or in some cases be achieved nonthyroidal illness TgAA. polyvalent vaccine research and vaccination of dogs with rabies virus or rabies vaccine alone, the recent production of thyroglobulin autoantibodies, hypothyroidism led to the further development of an exciting and important finding with implications for the career.
Canine population of 287 948 study recently was published by the MSU Animal Health Diagnostic Laboratory. Circulating thyroid hormone autoantibodies (T3AA and / or T4AA)) 18 135 of these dogs (6.3%) are found. Pointer, English Setter, English Pointer, Skye Terrier, German Wirehaired Pointer, Old English Sheepdog, Boxer, Malta, Kuvasz, and Petit Basset Griffon Vendéen: study of the thyroid AA There were 10 breeds with the highest prevalence. Prevalence was related to body weight was greater in dogs 2-4 years old. Women's thyroid hormone AA In these puppies transplacentally as well as the ability of colostrum and with circulating thyroid males.A AA Women were often enough. In addition, AA Any dog ??thyroid thyroid disease and / or clinical symptoms develop could be susceptible to other autoimmune diseases. Thyroid screening for selection of potential breeders, and is very important for clinical diagnosis.
Thyroid testing for genetic selection is likely to be less meaningful before puberty. Investigation was launched, the once healthy dogs and females have reached sexual maturity (10-14 months in males and anestrus after summer with her maiden name first among the women). Anestrus as the female sexual cycle alone, based on the effects of sex hormones on thyroid function is low.
The period usually begins 12 weeks after the beginning of last summer and lasts a month or longer. Women remain more reliable when interpreting the results of profiles of thyroid tested in anestrus. In fact, intact females for other disorders, such as genetic screening is planned, von Willebrand (VWD) disease, hip dysplasia and Czech-ups or breeding (vaginal cultures, hormone testing) is best during anestrus welfare. Once the initial thyroid surgery, dogs and bitches profile for an annual assessment of thyroid function and overall health are based on the need to reevaluate. Than the production of an annual test results that can develop early detection of thyroid disease offers. It is early treatment where indicated or prevent the occurrence of clinical symptoms of hypothyroidism associated with progression allows for.
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